Lynch syndrome, or hereditary non-polyposis colorectal cancer (HNPCC), is the most common cause of inherited colorectal cancer, accounting for 3% of all cases. It is an autosomal dominant condition characterized by germline mutations, most commonly MLH1, MSH2, MSH6, and PMS2, or deletions in the EPCAM gene, which leads to microsatellite instability (MSI). This elevates the lifetime risk of malignancies such as colorectal, endometrial or ovarian cancer. Early-onset colorectal cancer with ascending colonic lesions are characteristics of lynch syndrome. We are presenting an unusual case of descending colo-colonic intussusception in a young gentleman, who has a significant family history of lynch syndrome.