1111 posters, 
16 sessions, 
755 authors
ePostersOnline®, by the PosterGenius® team

EP1.60

Use of fetal fibronectin testing in a District General Hospital in women with symptoms of preterm labour

Monday, 24 June, 2013 - 13:48
Board 02

                      Use of Fetal Fibronectin Testing in a District General Hospital in Women with Symptoms of Preterm Labour
                                                                                     Myint, H.H., Ciopec, A., Roberts, N. & Sinha, P.
                                                                   East Sussex Healthcare NHS Trust, St.Leonards-on-Sea, United Kingdom
 
 
AIMS:
To evaluate the use of fetal fibronectin (fFN) testing within a District General Hospital setting and to review the fFN positive and negative predictive values in women presenting with symptoms of preterm labour. 
 
METHODS:
Retrospective case note review of all women having a fFN test at East Sussex Healthcare NHS Trust from May 2010 to April 2011 (n=166). Data collected included risk factors for preterm labour, signs and symptoms, antenatal management, number of fFN tests performed and gestation at delivery.
 
RESULTS:
 
ØA total of 174 fFN tests were performed on 166 women.
Ø 5% of women (9/166) had the test performed more than once.         
ØThe percentage of negative results was 80% (140/174) and the percentage of positive results was 20% (34/174).      
ØThere were 33 women (19%) with positive results and 133 women (81%) with negative results. 
Ø Three of the 33 women (9%) with a positive fFN result delivered within 10 days of the test compared with two of the 133 women (1.5%) of the women with a negative result. 
ØTocolysis was not given to any woman who had a negative result.
ØHospital admission was avoided in 84.9% of women (113/133) with a negative result.
ØCorticosteroids were given to 5.2% of women (7/133) despite a negative fFN result.
ØIn those women with a positive fFN, 25 out of 33 received corticosteroids and 25 out of 33 were admitted. Tocolysis was given to 2 out of 33 women with positive results and 7 out of 33 women with a positive result had in-utero transfers.
 
CONCLUSION:
 
The use of fFN in this Trust allows management and resources to be targeted to those women at highest risk of preterm birth. Our results show positive and negative predictive values that are comparable to other studies. Implementation of fFN testing has shown a significant reduction in the use of steroids, tocolysis, inpatient stay and in-utero transfer.
 
 
                                                                     Source of Funding: East Sussex Healthcare NHS Trust