Title: ANALYSIS OF NEW HIV INFECTED CHILDREN DURING THE LAST SEVEN YEARS IN THE

SPANISH COHORT OF HIV-INFECTED CHILDREN (CORISPE)

Background: In the last years,the rate of new HIV-infected children have decreased in

developed countries because of a combination of public health interventions such as a

widespread routine HIV testing and prophylaxis to avoid vertical transmission.Some of these ne

pediatric HIV diagnoses correspond to children born in developing countries.

Methods: A crosssectional

study was performed.Data were collected from all children at the Spanish Cohort of

HIV-infected children (CoRISpe) who had been diagnosed with HIV infection in the last seven

years (January 2005-December 2011).Demographic,clinical,immunologic and virologic data wer

collected.

Results: Up to now CoRISpe has recruited 838 patients.During the study period 156

patients were new diagnoses.136 (87,2%) were vertically infected. 73 (53,7%) were female.At

the diagnosis the median age was 1,6 years (IQR: 4,9-0,18). 30 (22,1%) were C.Median %CD4

was 23 (IQR: 33-15,25),median CD4/mm3 930 (IQR: 479-1740),viral load 170000 copias

(IQR:30399- 545750). 9 patients (6,6%) were coinfected by other viruses or pathogens as HBV

(2,9%),CVM (2,9%) or syphilis (0,8%). 80 (58,8%) were born in Spain. 82 (60,3%) were born of

an immigrant mother or father.The nationality of the foreign parents were Sub Saharan Africa 53

(64,6%),Central and South America 11 (13,4%),Eastern Europe 6 (7,3%),North Africa 7

(8,5%),Europe 3 (3,7%),Asia 2 (2,4%).

Conclusions: Despite the prophylactic measures taken t

avoid vertical transmission of HIV there have been few new cases of infected children born in ou

country.Furthermore, we had some cases whose infection was vertically-acquired in another

country and, therefore, we should consider this possibility in order to avoid a delayed diagnosis

in foreign children.

Paediatric HIV