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Urinary stone composition in a developing country: evolution through 12 years.


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Urinary stone composition in a developing country: evolution through 12 years.
 
 
Introduction: change in incidence and urinary stone composition has been reported in industrializad countries. However, current latin american data in stone disease is lacking. We present the result of a study bases on 2864 caluli analized during 12 years.
 
 
Methods:
We collected data from Catholic University Hospital database over the period from January 1, 2001 to December 31, 2012. These records included kidney stone composition, gender, age and location where the samples were collected.
Using time series statistics, the monthly data was analyzed in order to calculate the rate of change of the kidney stone composition pattern.
Demographic data was compared using unpaired Student's t-test. Pearson's Chi-squared test was used for inferences on proportions.
 
Results:
Basic demographic data is presented in Table 1.
Figure 1 shows a time series plot of all monthly kidney stone composition data. When we studied all samples, the cases appear to be drifting downward during the period 2000s to mid-2004s (from 19.1 to 12.9 cases/month on average), to later increase reaching 26 cases/month on average (lowess smoothing). By gender, female cases slowly rose from 5 cases/month on average (period 2000s-2006s) to almost 10 cases/month (cases grew at an average annual rate of 3.3% for the entire period). On the other hand, controlling for non-stationality of the data (up and down drifting), male cases did not show a significant change.
The percentage distribution of the kidney stone composition by age is presented in Figure 2.
 
Conclusions:
 
The behavior of urinary stone composition remains stable through the analized period and between group of ages as well.  Incidences increases in our population is similar to previously reported in developed countries, specially in female group. This might be due to changes in obesity rates and dietary habits related to socioeconomic modification ocurred in our country, specially in the last decade.