77 posters, 5 topics, 469 authors, 212 institutions

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Posters

4.27

RESTORING HEMOSTATIC BALANCE IN HEMOPHILIA BY RNAi TARGETED SILENCING OF ANTITHROMBIN

Benny Sorensen, ALFICA SEHGAL, JUNE QIN, TIM RACIE, SCOTT BARROS, LACRAMIOARA IVANCIU, RODNEY` CAMIRE, YESIM DARGAUD, CLAUDE NEGRIER, AKIN AKINC

Alnylam Pharmaceuticals, Cambridge, MA, USA, Children’s Hospital of Philadelphia, USA, Hopital Edouard Herriot, Lyon, France

Poster Presenter: Benny Sorensen

4.28

Induction of tolerance to FVIII using nanoparticles in a murine model of hemophilia A

Aihong Zhang, Robert Rossi, Aaron Griset, Roberto Maldonado, Takeshi Kishimoto, David Scott

Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA, Selecta Bioscience, Inc., Watertown, MA 02472, USA, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA

Poster Presenter: David Scott

5.01

Inhibition of complement-mediated thrombotic microangiopathy with Eculizumab improves hematologic and renal outcomes in adult patients with aHUS.

Spero Cataland, Christophe Legendre, Enrico Minetti, Mario Espinosa, Jan Menne, Francois Provot, Eric Rondeau, Piero Ruggenenti, Masayo Ogawa, Fadi Fakhouri

Department of Internal Medicine, Ohio State University, Columbus, USA, Department of Renal Transplantation, Hospital Necker and University Paris Descartes, Paris, France, Department of Nephrology and transplantation, Careggi University Hopital, Florence, Italy, Department of Nephrology, Hospital Universitario Reina Sofía, Cordoba, Spain, Department of Nephrology and Hypertension, Hannover UMedical School, Hannover, Germany, Department of Nephrology, University Hospital of Lille, France, Department of Nephrology, Tenon Hospital, Paris, France, Istituto di Ricerche Farmacologiche Mario Negri, Bergamo, Italy, Clinical Development, Alexion Pharmaceuticals, Cheshire, USA, Department Nephrology and Immunology, University Hospital Nantes, Nantes, France

Poster Presenter: Spero Cataland

The Poster has not been submitted by the Author.

5.02

Complement regulatory components in patients with atypical hemolytic uremic syndrome in Iran

Soudabeh Hosseini, Akbar Dorgalaleh, Ebrahim Kalantar, Nakisa Hooman, Saeed Dorgaleleh, Bamedi Taregh

Hematology and flowcytometry Laboratory Ali Asghar Children hospital, Iran University of Medical Sciences, Tehran, IranLaboratory director, Gholhak clinical Laboratory, Tehran, Iran, Department of Hematology, School of Allied Health Science, Iran University of Medical Sciences, Tehran, Iran, Hematology and flowcytometry Laboratory Ali Asghar Children hospital, Iran University of Medical Sciences, Tehran, Iran, Paediatric Nephrology Ward , Ali Asghar Children hospital, Iran University of Medical Sciences, Tehran, Iran, Department of Laboratory Sciences, Zabol University of Medical Sciences, Infection diseases and tropical medicine research center, Zahedan University of Medical Sciences, Zahedan, Iran

The Poster has not been submitted by the Author.

5.03

Early Volume Expansion for Mitigating Shigatoxin-Associated Hemolytic Uremic Sindrome. Data of the North Italian HUS Network.

Gianluigi Ardissino, Francesca Tel, Sara Testa, Stefania Salardi, Rosaria Colombo, Ilaria Possenti, Silvana Tedeschi, Erminio Torresani

Center for HUS prevention, control and management, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy for the North Italian HUS Network

5.04

The role of ADAMTS13 in DVT: In vitro characterization of ADAMTS13 Single Nucleotide Variants identified by next-generation sequencing in a group of Italian DVT patients

Maria Teresa Pagliari, Luca Andrea Lotta, Carla Valsecchi, Gloria Casoli, Paolo Bucciarelli, Ida Martinelli, Frits R. Rosendaal, Flora Peyvandi

Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center Milan, Italy, Department of Clinical Epidemiology and Department of Thrombosis and Haemostasis, Leiden University Medical Center, Leiden, the Netherlands, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center Milan, Italy, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy

Poster Presenter: Maria Teresa Pagliari

5.05

ANTI-TAIL MONOCLONAL ANTIBODIES CHANGE THE CONFORMATION OF ADAMTS13 INTO A HYPERACTIVE STATE

Louis Deforche, Elien Roose, Aline Vandenbulcke, Li-Zhi Mi, Hanspeter Rottensteiner, Tim Springer, Hans Deckmyn, Simon De Meyer, Karen Vanhoorelbeke

Laboratory for Thrombosis Research (LaTrOn), IRF Life Sciences, KU Leuven kulak, Kortrijk, Belgium, Program in Cellular and Molecular Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA, Baxter Innovations GmbH, Vienna, Austria, Program in Cellular and Molecular Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA, USA

Poster Presenter: Louis Deforche

5.06

The chemical chaperone betaine leads to increased secretion of an ADAMTS13 secretion defect mutant

Mary Underwood, Flora Peyvandi, Isabella Garagiola, Samuel Machin, Ian Mackie

Haemostasis Research Unit, University College London, London, EnglandDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy., Haemostasis Research Unit, University College London, London, England., Angelo Bianchi Bonomi Hemophilia and Thrombosis Centre, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy, Haemostasis Research Unit, University College London, London, England

Poster Presenter: Mary Underwood

5.07

Dense genotyping of immune-related disease regions for the identification of genetic risk factors in acquired thrombotic thrombocytopenic purpura.

Ilaria Mancini, Andrea Cairo, Marcin Gorski, Barbara Ferrari, Luca Lotta, Isis Ricaño-Ponce, Cisca Wijmenga, Flora Peyvandi

Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico and Luigi Villa Foundation, Milan, Italy, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy, Genetics Department, University Medical Center and University of Groeningen, Groeningen, The Netherlands, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico and Luigi Villa Foundation, Milan, Italy, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy

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